DNA sequencing technique and applications

DNA sequencing

What is DNA sequencing? ”DNA sequencing is a technique of biotechnology to determine the genome sequence with precise nucleotide order within it.” Determination of precise sequence and order of DNA bases: adenine, guanine, cytosine and thymine is performed. The purpose is to analyze and compare the genetic makeup of individuals. Moreover, it has significance in …

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Plantibodies for therapeutic purposes

Plantibodies

As the name suggests, plantibodies are class of antibodies, which are derived and generated in plants. Although mammalian cells are main source of engineered antibodies production, yet plants also can serve the same purpose as well. Plant biotechnologists aims to manipulate the natural abilities of plants for production of engineered antibodies for therapeutic purposes. Why …

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Nutritional biochemistry and metabolism

Nutritional biochemistry

The branch of science that interprets or explains the relationship of food with the functioning of living system is nutritional biochemistry. Nutrition refers to all kind of nourishment that is helpful for sustainability of life. The study of nutrient requirement and the diet that provides these nutrients is also termed as nutrition. So, the nutrition …

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Mechanism of epigenetic modifications

Epigenetics

Epigenetic modifications are stable heritable traits or phenotypes other than those which are based on genomic sequences. There are dynamic event that modulate the gene expression. These are functionally relevant changes and modifications of genome that excludes modifications of nucleotide sequences. For example, the mechanisms of histone modifications, DNA methylation, acetylation etc that effect the …

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bacterial transformation and selection of cells

Bacterial transformation and selection

Transformation is a basic technique of biotechnology to develop transformed cells (bacterial, plant or animal cell) containing a foreign DNA fragment in their genome. The foreign DNA incorporates in cellular genome in such a way that genes of foreign DNA express themselves. Therefore, the organism or cell is termed as transformed cell. Consequently, the transformed …

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The history of genetics

History of genetics

 The study of inheritance of traits from organism to its offspring and the way these traits are inherited is termed as genetics. It includes study of hereditary matter DNA, its genes and also the variations in genetic material of the organisms. The concept of evolution and the natural selection of species as proposed by Darwin …

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Various types of Recombinant antibodies

Recombinant antibodies

The B cells of adapted immune system produces antibodies or immunoglobin molecules in response to foreign antigens. The emergence of recombinant DNA technology in 1970’s has led to the production of ‘engineered or recombinant’ antibodies (rAbs). Initially researchers tried their best for production of humanized antibodies and fragmentation of these Abs and it resulted in …

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How to prevent ovarian cancer?

Ovarian cancer is linked with genetic mutations and their inheritance in family. This makes some of us are at more risks of developing ovarian cancer than some others. Studies suggest that BRCA gene mutation is linked to ovarian cancer in young females.(brca-gene)  BRCA 1 & BRCA 2 genes are tumor suppressor genes. Mutation in these …

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Cherries a must have of balanced diet

8 Health benefits of cherries

Cherry fruit comes from plants of genus prunus and a fleshy drupe (stone fruit). These are of various types such as bright red sour, dark Hudson, rainier  and yellow cherries. As raw fruit, these provide little nutrient content per 100 g serving (nutrient table). Overall, cherries are enriched with dietary fibers and vitamins.  Compared to …

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Significance of autophagy

Autophagy

Autophagy is the controlled digestion and degradation of damaged and old cell and its components. Form the Greek origin, “auto” mean “self” and “phagein” refers to “eat”. In the process, the cell can digest its own components by enclosing them in a membrane forming sac-like vesicles. These are later transported to lysosome. Lysosome  is the …

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BRCA gene mutation and links to breast cancer

BRCA gene

Gene is a particular sequence of nucleotide which codes for a protein product. BRCA gene is abbreviation for BReast CAncer gene. BRCA 1 and BRCA 2 genes have association with developments of breast cancer in humans. Both of BRCA gene prevent cancer development in normal functional state. These are not only tumor suppressor gene but …

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Natural vs. synthetic vitamins sources

Natural Vs. synthetic vitamins

Vitamins are essential to maintain a good health. Our daily diet must have substantial portion of vitamins and minerals. Most of us opt for synthetic vitamin supplements to fulfill their nutritional. However, are the synthetic vitamin supplements worth using and completely safe for consumer’s use? This article may help you all to decide what’s the …

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Health benefits of oregano oil

Oregano oil

Oregano oil is extracted from leafs of herbaceous oregano plant. (Scientific name: origanum vulgare). This oil a rich source of natural vitamins and minerals such as calcium, magnesium and phosphorous, copper. All of these boost up the immune system. Moreover, it has volatile components, caravacrol and thymol which have great anti-inflammatory, antimicrobial and antiviral properties. …

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Few tips to relive flu symptoms

Treating flu at home

Having flu, is no doubt makes us miserable with each of its symptoms from coughing, sneezing and having a clogged nose contribute equally in making it worse. Flu is a respiratory system infection characterized by sneezing, coughing, clogged nose and heavy breathing. This is caused by influenza virus. The virus is contagious and it spreads …

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